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  • 3M™ Emphaze™ AEX Series Hybrid Purifier, BV360R, EMP533AEX020R, Scale-Up, 1/Case
  • 3M™ Emphaze™ AEX Series Hybrid Purifier, BV360R, EMP533AEX020R, Scale-Up, 1/Case

    3M ID 7100158435UPC 00638060374757
    • Reduces turbidity, HCP, DNA and bioburden
    • Excellent throughput and mAb recovery
    • Enhanced capture column performance and protection
    • Substantial turbidity, DNA, HCP and bioburden reduction.
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    Spesifikasjoner
    Bransjer
    Biovitenskap
    Bruksområder
    Adsorptiv dybdefiltrering, Reduksjon av biobyrde, Klargjøring av cellekultur, Kromatografi og kolonnebeskyttelse, Fjerning av DNA, Plasmafraksjonering
    Dimensjoner (Metrisk)
    15.2 cm x 21.6 cm
    Filter Material
    Helsyntetisk hybrid
    Filtertype
    Filterkapsel
    Flowfrekvens (Metrisk)
    300 Millilitre per Minute
    Lager temperatur
    68
    Maksimal driftstemperatur (Celsius)
    40 Degree Celsius
    Mirkonrate
    0,2 μm
    Produktserier
    AEX
    Serie
    Emphaze™ AEX Series
    Units per Case
    1
    Varemerke
    Emphaze™
    Produktdetaljer
    • Reduces turbidity, HCP, DNA and bioburden
    • Excellent throughput and mAb recovery
    • Enhanced capture column performance and protection
    • Substantial turbidity, DNA, HCP and bioburden reduction.
    • Reduced surface area requirement of the downstream sterilizing grade membrane.
    • May offer differentiated protection of the protein A column for enhanced contaminant clearance performance.
    • All product components comply with United States Pharmacopeia (USP) Class VI 70°C Biological Reactivity Tests, in vivo.

    3M™ Emphaze AEX Hybrid Purifier is our single-use sterilisable and sanitisable. The all-synthetic purification media that contains a Q-functional anion exchange media and a fine particle and bioburden reduction membrane.

    Remove impurities in biopharmaceutical process streams such as DNA, host cell proteins (HCP) and viruses with our all-synthetic, single use 3M™ Emphaze AEX Hybrid Purifier. The composite purification media is comprised of three primary components: anion exchange nonwoven, microporous membrane, and membrane support. The anion exchange media is composed of four layers of polypropylene nonwoven with a covalently attached quaternary ammonium functional polymer. The bioburden reduction membrane is a highly asymmetric polyamide membrane which has nine zones of decreasing pore size, spanning approximately a 20 X range, and terminating with a 0.2 μm rated qualifying layer. This is followed by a polypropylene nonwoven used as a support layer in the capsule. Capsules There are two primary capsule configurations for the Emphaze AEX Hybrid Purifier, Laboratory and Scale-up capsules: - The Laboratory capsule (BV8) has an 8ml bed volume - The Scale-up capsules are constructed from a lenticular media cell design having bed volumes of 120 mls and 360 mls (BV 120 and BV 360 respectively) - The Production capsules are scaled to meet your manufacturing requirements and utilise manifolds in a holder for ease of use A full support package is available for 3M Emphaze AEX Hybrid Purifiers. This package includes Installation and Operation Guides, a Certificate of Quality and a Regulatory Support File.

    Foreslåtte applikasjoner

    • Use for the clarification of mammalian cell cultures and to optimise downstream processes for monoclonal antibodies (mAbs)